Pentosan Polysulfate (PPS) Joint Pain, Inflammation and Cartilage Support PPS is a regenerative therapy used to help: Decrease joint pain and stiffness Improve mobility and function Support cartilage repair Reduce inflammatory cytokines in joints It is commonly used for osteoarthritis, chronic joint discomfort and other inflammatory musculoskeletal conditions
doi:10.1177/0269881117741766CrossRefGoogle ScholarPubMed Koomar, T, Thomas, TR, Pottschmidt, NR, Lutter, M, Michaelson, JJ
A larger 228-adult double-blind, randomized, placebo-controlled, dose-ranging trial in functional constipation (Rome III criteria) tested 1 10 and 1 10 CFU per day for 28 days against placebo
When administered appropriately under medical supervision, side effects may include dehydration, hypocalcemia (low calcium levels), renal impairment, elevated liver enzymes, electrolyte imbalance, and allergic reactions
Exogenous AntioxidantsDouble-Edged Swords in Cellular Redox State Health Beneficial Effects at Physiologic Doses versus Deleterious Effects at High Doses