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The Phases of Liver Detoxification Phase I Liver Detoxification: Biotransformation Phase I detoxification is the primary step in the detoxification process and involves the modification of various substances through oxidation, reduction, hydrolysis, hydration, and dehalogenation reactions

J Neuroimmunol 102:113124 Bateup HS, Svenningsson P, Kuroiwa M et al (2008) Cell type-specific regulation of DARPP-32 phosphorylation by psychostimulant and antipsychotic drugs