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The pharmacokinetics of flutamide and its major metabolites after a single oral dose and during chronic treatment

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Interestingly, disrupting 3D cells and growing them in adherence reversed this occurrence of resistance, confirming the notion of CSCs plasticity, which maintains that cancer cells have the dynamic potential to switch between a CSC state and a non-CSC state

A total of 44 biomarkers were classified into more than one category