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Treatment with FOXO4-DRI reduces hydroxyproline content in lung tissue, a direct measure of collagen deposition, and improves lung histology assessed by hematoxylin-eosin and Masson trichrome staining

Follow-up bloodwork should occur at 8 to 12 weeks after starting therapy, then quarterly during ongoing use

Supports angiogenesis by increasing VEGF expression, which improves blood supply and nutrient transport

(2010) 44:e149

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