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current strategies often disrupt normal mitochondrial function in healthy tissues, and biomarkers to stratify patients likely to respond to such therapies (based on mitochondrial ferroptosis signatures) are still absent

Research indicates that it serves as a crucial fuel source for lymphocytes and other immune cells, helping maintain optimal immune responses

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The HOMA-IR index was calculated as the product of basal glucose (mmol/L) and insulin levels (U/mL) divided by 22.5 [16-17]