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Adding gastric inhibitory polypeptide (GIP) receptor agonists amplifies the gastric effects of GLP-1s, as the higher weight loss promised by the dual action tirzepatide, compared with semaglutide, exemplifies 2

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Loading phase: For patients without neurological involvement, the standard regimen is 1 mg hydroxocobalamin intramuscularly three times weekly for two weeks (total of six injections)