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Patients with asthma represent a relative contraindication group, as bronchospasm has been reported in susceptible individuals following parenteral administration

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Single doses of mGluR1 antagonist (JNJ16259685) and fenobam rescued social and repetitive behaviors in eukaryotic initiation factor 4E-binding protein 2 gene ( Eif4ebp2 ) knock-out mice [155], implying that group I mGluRs are a favorable therapeutic target for ASD

Many studies show that these supplements are ineffective at raising glutathione levels in the body and inside cells