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However, a common hurdle many people face is semaglutide constipation

When combined with diet and exercise changes, Ozempic may lead to more significant weight loss over the long term

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"Patients may also notice their genital region more with weight loss if it was previously hidden by significant fat in the pubic and lower abdominal region." Not only can volume loss change the appearance of these structures, but loose skin can also cause discomfort, chaffing and irritation