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Likewise, fully maintained spatial learning and memory of the rats in the Morris water maze test was ascribed to hippocampal synaptic plasticity and NMDA receptor function [237] involving the entorhinal and perirhinal cortices, the prefrontal cortex, the cingulate cortex, the neostriatum, and perhaps even the cerebellum in a more limited way [237]

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The incidence is relatively low, affecting less than five percent of patients with pre-existing retinopathy, but regular ophthalmologic monitoring is recommended for patients with diabetes-related eye disease