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In microglia, GLP-1R activation via PI3K/Akt signaling also reduces neuroinflammation by modulating NF-B activity, decreases the production of pro-inflammatory cytokines, increases anti-inflammatory markers such as IL-10, IL-4, Arginase, and CD206, and the transformation of microglia into an anti-inflammatory state

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The consistent growth in deal size underscores the high stakes and escalating competition in the obesity drug market

Since this process changes how your digestive system acts, common side effects include nausea, constipation, and other types of stomach discomfort

It also improves blood flow and angiogenesis, which helps with tissue repair