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The peptide is a SNAP-25 mimetic designed to competitively inhibit SNAP-25 incorporation into the SNARE complex, modulating neurotransmitter release at the neuromuscular junction

An orally available NNMT inhibitor if the animal bioavailability data translates to humans would have significant practical advantages

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[1] [6] However, injectable therapy remains the first-line treatment in UK practice for pernicious anaemia and severe deficiency, as it bypasses absorption issues entirely