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Participants on the 12 mg dose reached roughly 24% mean body-weight reduction from baseline, the largest figure reported for an incretin-based compound in a trial of this length [1]

NICE recommends semaglutide for weight management only within specialist weight management services and under more restricted BMI criteria than the MHRA licence

Rosmaninho-Salgado, J., Marques, A

Protein-based vaccines can consist of a protein purified from the virus or virus-infected cells, recombinant protein or virus-like particles

Results were sobering: participants regained an average of 65% to 70% of their initial weight loss within 12 months