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Lactate production by perifused muscle tissue Muscle fragments (6 2 mg each) were placed into each of six channels of a commercially available perifusion system (BaroFuse) operating at a flow rate of 30 L/min of KRB with 0.1% BSA and varying amounts of glucose

Proc Natl Acad Sci U S A (2012) 109:797481.10.1073/pnas.1120210109 28 FryeREMelnykSMacfabeDF

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epidermidis compound responsible for GLP-1 stimulatory activity To identify the bacterial component responsible for GLP-1 secretion in vitro and for metabolic disease marker modulation in vivo , we performed size fractionation studies on conditioned supernatants of S