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Semaglutide has been shown to improve liver labs, modulate lipid metabolism, and lower hepatic inflammation, with effects that appear at least partly independent of weight loss

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Four of 130 (3%) patients treated with rosuvastatin (2 treated with 10 mg and 2 treated with 20 mg) had increased CK greater than 10 x ULN, compared to 0 of 46 patients on placebo

If these appetite changes are absent, dose escalation is necessary

Injectable semaglutide makes you feel fuller faster, and helps you stay feeling full longer, so you may find yourself eating smaller portions that you were before