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Targeting inflammasome activation, inhibiting caspase-1, employing anti-inflammatory agents, and modulating the gut microbiota and bile acid metabolism represent promising avenues for developing novel treatments for this common and potentially life-threatening condition

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The SDB-RPS StageTip was first conditioned sequentially with 100 l of 100% methanol, 100 l 50% acetonitrile with 0.1% formic acid and two washes of 100 l of 0.1% formic acid