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[31] It transports ferrous iron out of the cell, generally aided by ceruloplasmin and/or hephaestin (mostly in enterocytes), which oxidize iron to its ferric state so it can bind ferritin in the extracellular medium

IGF-1 injections are used to treat conditions like growth hormone deficiency or muscular dystrophy

Management of hyperglycemia in type 2 diabetes, 2015: a patient-centered approach: update to a position statement of the American Diabetes Association and the European Association for the Study of Diabetes

After 2-3 months, fine lines around the mouth and eyes may begin to disappear

Intracellular irons are tightly bound to either proteins or small molecular ligands and sequestered in specific pools to avoid toxic effects