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DESCRIPCIN Los desequilibrios en el metabolismo pueden provocar acumulacin de grasas, dificultad para controlar el apetito, prdida de masa muscular o alteraciones de la glucemia

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If an individual in mid-life has a pro-neurodegenerative microbiome signature (low diversity, low SCFA-producers, high pro-inflammatory taxa), they might be counseled to intervene early via diet, prebiotics, or even prophylactic probiotics to shift their microbiome to a healthier state

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Lower energy expenditure: Resting metabolic rate decreases with weight loss as the body adapts and both lean and fat mass are reduced