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Both medications are GLP-1 receptor agonists

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The FDA prescribing information advises patients using oral hormonal contraceptives to switch to a non-oral birth control method or add a barrier method for 4 weeks after starting tirzepatide and for 4 weeks after each dose increase

The sublingual formulation enhances the medications effectiveness by allowing for swift absorption into the bloodstream, resulting in faster impacts on appetite regulation and reducing gastrointestinal side effects commonly associated with oral GLP-1 agonists