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In this study, we investigate this question by examining a region-specific knock-out mouse line that lacks the NR1 gene, which encodes the essential subunit of the NMDA receptors, in granule cells of the dentate gyrus (DG-NR1KO mice)
Outro ponto frequentemente abordado na literatura sua interao com os fibroblastos, clulas responsveis pela produo e manuteno de componentes estruturais da derme, como colgeno, elastina e glicosaminoglicanos
Wedelolactone inhibits caspase-1/11 activation and reduces IL-1 and gasdermin D levels, thereby alleviating pyroptosis, ferroptosis, and lung injury through glutathione peroxidase-4 (GPX4) mediation [106]
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