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These superantigens do not have to be stimulated by Langerhans cells, and they can activate many lymphocytes via non-specific receptors ( Briganti et al

Adsorption characteristics of N-rGO for multiple representative trace antibiotics in water

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Although upregulated glycolysis can temporarily support cell survival, the resultant accumulation of lactate and H+ alters local pH, undermines cartilage matrix homeostasis, and influences both amino acid and lipid metabolic pathways (101)