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(2013) showed that the activation of -Catenin could enhance the LEF1 transcription factor and contribute to the secretion of VEGF and IGF1, as well as to the growth cytokine enrichment

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HDACs, histone deacetylases

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These agents have been shown to reduce inflammation and oxidative stress by downregulating C1q, TNF-a and IL-1a, which are key contributors to neurodegenerative processes in the retina and optic nerve, the authors wrote