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In a murine sepsis model, LPS has been shown to suppress FAO by inhibiting the expression of associated genes, including CPT1 , in kidney and liver tissues

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36 (suppl 1)

Common reasons for treatment interruptions include: Medication supply shortages or availability issues Intolerable gastrointestinal side effects requiring a break Acute illness or surgical procedures Pregnancy or planning pregnancy (note: Wegovy must be discontinued at least 2 months before planned conception) Funding or prescription access changes Travel or lifestyle disruptions Recognising why the interruption occurred helps inform the restart strategy and prevents future discontinuations

Research consistently shows high-protein meals increase GLP-1 secretion by 50-100 percent compared to high-carbohydrate meals