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Further investigation revealed that mTOR inhibition drove the formation of lamellipodia, which relocated mitochondria away from the plasma membrane

Surprisingly, the incidence of T2DM in PWS individuals is lower than expected (165, 182), indicating they have a healthier metabolic profile compared to weight-matched healthy individuals

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Immune checkpoint inhibitor treatment HR+/HER2 breast cancer, the most prevalent subtype, exhibits limited sensitivity to neoadjuvant chemotherapy, with a pCR rate of ~10%