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Renal localization (proximal tubule): reabsorption: URAT1 (apical membrane), GLUT9 (apical and basolateral membranes), and OAT4/10 (mainly apical)

Importantly, we here demonstrate that the REW substitutions strongly attenuate binding to SpA (Fig S5r, s), and accordingly, IgG1-REW could efficiently engage C1q, even in the presence of 5-molar excess of SpA, which prevented binding to WT IgG1 (Fig

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The primary advantage of single-cell genomics lies in its ability to uncover intercellular differences, which is essential for understanding disease development mechanisms [268]

Acamprosate is a long-term treatment to help restore your brain after the damage done by drinking too much