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Since endogenous antioxidant enzymes or antioxidants are responsible for most of the bodys antioxidant capacity, strategies to enhance antioxidant-enzyme interactions for disease management involve increasing antioxidant activity or inhibiting ROS release to mitigate oxidative stress

67 In contrast to SOD1, SOD2 is inducible by oxidative stress, hyperoxia, environmental pollutants such as cigarette smoke or ozone, and by inflammatory cytokines

Emerging and established modes of cell death during acetaminophen-induced liver injury

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