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This process is potentially dangerous to cells, as peroxidation of mitochondrial phospholipids may affect the integrity of permeability transition pores (PTPs) and disaggregate complexes I and III of the respiratory chain, thereby enhancing electron leakage within the mitochondrial intermembrane space 5,6

Human leukemic cells: receptor binding and biological effects of insulin and insulin-like growth factors

Additionally, gene editing and RNA-targeting technologies offer hope for transformative therapies, though challenges remain in ensuring specificity, safety, and long-term efficacy [5558]