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Similar to the results obtained with acute injection, repeated liraglutide treatment (six injections over 2 weeks) of alcohol-experienced male rats has been shown to decrease both alcohol consumption and preference for alcohol (Vallof et al., 2015)

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In the SIS paradigm, a significant decrease in mitochondrial function-related genes, such as the COX-related genes, was revealed, whereas RES treatment increased the expression of COX genes (Cox5a, Cox6a1, and Cox7c) and the activity of COX [175]

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See Supplementary table 4A for details