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The gastrointestinal side effects common with GLP-1 initiationnausea, constipation, diarrheacan be harder to distinguish from UC symptom patterns

When, in the past, monitoring of symptoms had been done poorly, there may be some people who do not need parenteral B12 supplementation

While both doses were safe, participants on methylcobalamin did not experience a significantly slower functional decline, as assessed with the ALS Functional Rating Scale Revised (ALSFRS-R), than those on a placebo, failing to meet the studys main goal

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