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Acute administration of MK-801 in an animal model of psychosis in rats interferes with cognitively demanding forms of behavioral flexibility on a rotating arena

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Complete series of sections were immunohistochemically stained for BrdU/DCX and BrdU/NeuN to examine sex differences in the maturation timeline of new neurons, for Sox2 to examine the number of neural stem cells, and for Ki67 to examine actively dividing progenitor cells

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This is a common concern, borrowed from how suppressive hormones like exogenous testosterone behave