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Perspective Back to Top The approval of once-weekly semaglutide for adolescents aged 12 years and older marks another milestone and a big step forward for the treatment of obesity in the pediatric population

, Glucagon-like peptide-1 therapy in people with obesity restores natural killer cell metabolism and effector function, Obesity , vol

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Hydration strategies: Aim for 6-8 glasses of fluid daily (about 1.5-2 litres), adjusting for activity level, climate and individual needs Sip fluids regularly throughout the day rather than consuming large volumes at once Monitor urine colour as a hydration indicatorpale straw colour suggests adequate hydration Consider oral rehydration solutions if experiencing diarrhoea or vomiting Moderate alcohol intake, which can worsen dehydration Note that caffeinated drinks count towards your fluid intake, though you may wish to moderate these if they worsen symptoms Note : If you have a condition requiring fluid restriction (such as heart failure or kidney disease), follow your healthcare provider's specific guidance on fluid intake