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The receptor complex formation upon TGF-1 binding by TGFBR2 leads to the phosphorylation of TGFBR1 (ALK5), which in turn phosphorylates Smad2 and Smad3 forming a complex with Smad4 ( Figure 6 )

Whats the underlying theory right now

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But it doesnt stop there, the GT-1 also features three different rotating prisms, a fixed color wheel with CTO/CTB filters, and a frost for softening the beam

This is a clinical syndrome in which AS is a common pathology between macrovessels and microvessels in the cardiac, cerebral, renal, ophthalmic, and peripheral systems in patients with diabetes