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Unlike genetic resistance, these phenotypes enable fungal cells to survive high concentrations of antifungals without a measurable increase in minimum inhibitory concentration (MIC), contributing to chronic and relapsing infections ( Cryptococcus can enter a quiescent state that confers high tolerance to AmB (Ke et al., 2024)

It is believed that the blood pressure reduction caused by tirzepatide results from various factors such as weight loss, vasodilation, natriuresis, concurrent medication, and reduction in extracellular volume [102]

In the first two weeks, you might experience mild bloating, gas, or a change in bowel habits