doi:10.1038/ejcn.2017.132 Weschawalit S, Thongthip S, Phutrakool P, Asawanonda P
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AMPK also serves a role in regulating lipid and protein metabolism by inhibiting the generation of transcription factors that bind to sterol regulatory elements, suppressing the synthesis of lipid biosynthetic enzymes in tissues, inhibiting fat synthesis, increasing fatty acid oxidation and reducing lipid accumulation (173)
The drug's primary actions on GLP-1 receptors do not appear to involve effects on the gastrointestinal mucosa that would predispose to bleeding