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Agents, such as metals, polysorbate-80 (PS-80), etc., are used to shrink the endothelial cells of the brain

The release of hemoglobin and iron from red blood cells activates macrophages, leading to the production of inflammatory factors including interleukin-1, interleukin-6, and tumor necrosis factor-alpha (22) and fostering the formation of damaging reactive oxygen species (23)

The comet assay data from the identified publications were subsequently entered into a Microsoft Access database

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