How do GLP-1s function differently than some of the drugs we've seen rise and fall in the past
Studies have shown that erastin and sulfasalazine can interfere with cystine absorption by inhibiting system Xc- activity, causing a reduction in GSH synthesis and a decrease in GPX4 activity, thereby inducing lipid peroxidation and cell death [24]
10.1016/j.devcel.2024.03.018 Dev Cell
Franklin J, Marra C, Abebe K, Butte A, Cook D, Esserman L, Fleisher L, Grossman C, Kass N, Krumholz H , Rowan K, Abernethy A, Abbasi A, Abebe K, Abernethy A, Adam S, Angus D, Ard J, Bender Ignacio R, Berkwits M, Berry S, Bhatt D, Bibbins-Domingo K, Bonow R, Bonten M, Brangman S, Brownstein J, Buntin M, Butte A, Califf R, Campbell M, Cappola A, Chiang A, Cook D, Cummings S, Curfman G, Esserman L, Fleisher L, Franklin J, Gonzalez R, Grossman C, Haddad T, Herbst R, Hernandez A, Holder D, Horn L, Huang G, Huang A, Kass N, Khera R, Koroshetz W, Krumholz H, Landray M, Lewis R, Lieu T, Malani P, Martin C, McClellan M, McDermott M, Morain S, Murphy S, Nicholls S, Nicholls S, O'Dwyer P, Patel B, Peterson E, Prindiville S, Ross J, Rowan K, Rubenfeld G, Seymour C, Taylor R, Waldstreicher J, Wang T
As more people turn to medications like Ozempic and Wegovy for weight loss or blood sugar issues, its only natural to want to know what to expect
