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5-Amino-1MQ is a small molecule membrane-permeable inhibitor of the enzyme Nicotinamide N-methyltransferase (NNMT)

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In addition, oleanolic acid and -sitogluside also have good affinity to the target proteins

Cyanocobalamin is indicated for vitamin B 12 deficiencies due to malabsorption which may be associated with the following conditions: It may be possible to treat the underlying disease by surgical correction of anatomic lesions leading to small bowel bacterial overgrowth, expulsion of fish tapeworm, discontinuation of drugs leading to vitamin malabsorption (see Drug Interactions), use of a gluten-free diet in nontropical sprue, or administration of antibiotics in tropical sprue