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This hyperphenylalaninemia is also thought to inhibit the transport of large neutral amino acids across the brain, decrease protein synthesis within the brain, and increase myelin turnover with eventual hypomyelination, all processes that may or may not contribute to the development of autism (56, 57)

Although such impacts have not been observed clinically, some experts warn that they could arise with wider use over extended periods

Wilcox et al., 2024)

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