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doi:10.1016/j.cmet.2018.03.001 Holst JJ, Rosenkilde MM

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Receptor Supersensitivity Blockade In the landmark 1997 Sikiric study published in Biological Psychiatry (PMID: 9547930), mice pretreated with haloperidol (a dopamine antagonist) developed behavioral supersensitivity to amphetamine challenge

3.1.2 Role of Nrf2/HO-1 pathway in ferroptosis and antioxidant defense The Nrf2/heme oxygenase-1 (HO-1) pathway plays a central role in oxidative stress-induced ferroptosis