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Similar content being viewed by others Introduction Over 38% of the global population is currently overweight or obese, a number predicted to grow to 51% by 2035 1

10.1038/s41419-023-05716-0 29 ChengY.QuW.LiJ.JiaB.SongY.WangL.et al (2022)

According to the mechanism study, baicalein could downregulate downstream important glycolytic enzymes (HK2, LDH-A, PDK1) by encouraging the accumulation of intracellular PTEN and inhibiting the activation of the PI3K/Akt signaling, thereby reversing the hypoxia-induced 5-Fu resistance (115)