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La acetilcarnitina es degradada por las esterasas plasmticas y usada por el organismo para transportar cidos grasos dentro de la mitocondria

Experimentally, the cellular GSH pool can be reduced by treatment with different oxidants such as hydrogen peroxide (H 2 O 2 ), tert -butyl hydroperoxide [238, 239], or diamide [240, 241]

Due to role of BLVRB in the pharmacodynamics of methylene blue, methylene blue treatment may be unsuccessful in BLVRB-deficient patients, as reflected in European Union drug labeling, which contraindicates the use of the drug in these individuals [2,3,112,113]

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