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[8] Although not an absolute contraindication, patients with coronary artery disease or unstable angina should only use B-Complex injections containing niacinamide under physician supervision, since high-dose niacin supplements have been linked to arrhythmias in such patients

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Following NEM or DMSO treatment, samples were incubated with a 2.3 M mixture of three activity-based probes: Biotin-Ahx-Ub-VME (UbiQ-054), Biotin-Ahx-Ub-PA (UbiQ-076), and Biotin-Ahx-Ub-VS (UbiQ-188), for 60 minutes at 300 rpm and 25 C