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Injectable formulations dominate the market with a 74% share, driven by their proven efficacy and reliability in delivering GLP-1 analogues

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Fatty acids are mainly taken up by proximal tubule cells through CD36

The proposed mechanisms include GLP-1 mediated changes in blood pressure regulation, effects on retinal and optic nerve blood flow, and potential interactions with cardiovascular risk factors that are common in the populations taking these drugs

With all the expanding possible indications, the GLP-1 peptides are being prescribed off-label for many purposes, and now people are microdosing the drugs despite the lack of data