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The mechanism by which semaglutide provides cardiovascular protection likely involves multiple pathways, including weight reduction, improved glycemic control, and blood pressure lowering

[159] suggested that xanthine significantly elevates the Th17/Treg ratio in AR via adenosine receptor a1 (Adora1)

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doi: 10.3389/fendo.2023.1133000 Received 28 December 2022 Accepted 13 March 2023 Published 24 March 2023 Volume 14 - 2023 Edited by Silvia Martina Ferrari, University of Pisa, Italy Reviewed by Sabrina Rosaria Paparo, University of Pisa, Italy