Yusta B, Baggio LL, Koehler J, Holland D, Cao X, Pinnell LJ, Johnson-Henry KC, Yeung W, Surette MG, Bang KWA, Sherman PM, Drucker DJ (2015) GLP-1R agonists modulate enteric immune responses through the intestinal intraepithelial lymphocyte GLP-1R
Only after comprehensive individual safety and efficacy profiles are established, and specific mechanisms of action are fully elucidated, can well-designed studies begin to explore potential synergistic combinations
In order to mirror chronic administration in clinical populations, the number of chronic dosage regimens in animal studies should also be enhanced
In addition, the composition and number of Firmicutes also affect secondary BA levels by altering 7-dehydroxylation (Lee et al., 2022)
Advocating for a broader understanding of the peptides health benefits beyond weight loss including treatment for PCOS, infertility, neuroinflammation, Alzheimers, and more