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Gastrointestinal cancers, including colorectal cancer, have been evaluated given the high concentration of GLP-1 receptors in the gut
These elements support the relation between this condition and systemic inflammation, due to the ethanol-mediated activation of nuclear factor-B (NF-B) signaling pathway, which could alter gut barrier integrity, increasing portal and systemic endotoxemia
The 4.2 / mice exhibit a hematological phenotype comparable to that of mild HS, which represents the phenotype of the majority of patients with this membrane disorder (1, 3)