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European Journal of Pediatrics January 1991, Volume 150, Issue 3, pp 205-208 16 Sklar R

Of the 14 semaglutide-treated patients that developed anti-semaglutide antibodies, 7 patients (0.2% of the overall population) developed antibodies cross-reacting with native GLP-1

The thigh may produce less nausea based on one clinical study, while the abdomen may provide slightly faster peak absorption