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Studies support that L-lysine can help decrease the frequency and duration of HSV cold sore outbreaks, by lowering levels of arginine (an amino acid that promotes HSV-1 replication) in the body, consequently suppressing HSV-1 growth

If you're prescribed cyanocobalamin injections, bring the following points to your doctor's attention

Neurological symptoms can include tingling or numbness in the hands and feet (peripheral neuropathy), a sensation often described as "pins and needles"

The loss of enterohepatic recirculation would definitely cause an additional loss of 5mcg of B12 that is not recovered from bile