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In some cases, drug therapy may begin with a combination of medications, such as metformin plus an SGLT2 inhibitor (which is available in a single pill for improved convenience)

Some individuals may experience mild digestive discomfort, nausea, bloating, or stomach upset, particularly when first introducing NAC-containing supplements

Kaseda ET, Levine AJ

Engraftment of mSOD1-astrocyte progenitors (which mature into astrocytes) into wild-type mice induced motor neuron death in the host ([80]

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