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Renewal requires documentation of clinical response, usually defined as at least 5 percent weight loss at 6 months or other clinical improvement matching the indication

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Lilly Rx Only NDC 0002-4052-11 Mounjaro (tirzepatide) injection 10 mg/2.4 mL (4.17 mg/mL) ATTENTION: Contains 4 doses of 2.5 mg/0.6 mL 2.4 mL MULTI-DOSE VIAL For Subcutaneous Use Needles and Syringes are not included Dispense enclosed Medication Guide to each patient

However, the oral bioavailability of semaglutide is only from 0.4 to 1% [93]