N-acetylcysteine ( NAC) and alpha lipoic acid (ALA) are also used to increase GSH levels
For example, Metabolon, a major commercial provider of metabolomics services widely used in the United States, employs a general metabolite panel and a more specific lipid-focused panel, which can lead to inconsistencies when comparing results across different platforms or timeframes (Germain et al., 2020)
[ Acknowledgements We thank Sven Paul, Institute of Animal Breeding and Husbandry, University of Kiel, for revising the manuscript, Matthias Leippe, Department of Zoophysiology, University of Kiel, for helpful information and Virbac for providing the picture "Internal organs of the horse"
Therefore, we measured malondialdehyde (MDA) content via thiobarbituric acid reactive substances (TBARS) assay to assess the state of lipid peroxidation as a measure for a shift in redox state toward pro-oxidant conditions that could cause oxidative stress
Collectively, these results indicate that KU-57788 promotes sustained mitochondrial fission in ATC cells by activating DRP1 through phosphorylation modulation, highlighting a potential mechanism by which KU-57788 regulates mitochondrial dynamics in ATC cells
